Peer review is a widely accepted instrument for raising the quality of science. Peer review limits the enormous unstructured influx of information and the sheer amount of dubious data, which in its absence would plunge science into chaos. In particular, peer review offers the benefit of eliminating papers that suffer from poor craftsmanship or methodological shortcomings, especially in the experimental sciences. However, we believe that peer review is not always appropriate for the evaluation of controversial hypothetical science. We argue that (...) the process of peer review can be prone to bias towards ideas that affirm the prior convictions of reviewers and against innovation and radical new ideas. Innovative hypotheses are thus highly vulnerable to being “filtered out” or made to accord with conventional wisdom by the peer review process. Consequently, having introduced peer review, the Elsevier journal Medical Hypotheses may be unable to continue its tradition as a radical journal allowing discussion of improbable or unconventional ideas. Hence we conclude by asking the publisher to consider re-introducing the system of editorial review to Medical Hypotheses. (shrink)

Discusses three concepts crucial to an understanding of the nature of religion: anxiety, guilt, and freedom. The various essays examine these from the viewpoint of several different religious traditions, movements and thinkers. Contents: Editor's Preface. Donald Gard: A Personal Perspective. Part I. Guiltless Morality; The Family of Changing Woman: Nature and Women in Navaho Thought; The Sacraments as "Fear-provoking" and "Awe-inspiring" Rites in the Greek Fathers; The Doctrine of Karma; Two Concepts of Predestination in Current Islamic Thought. Part II. The (...) Spirit of Medieval Penitents; The Evolution of Freedom as Catholicity in Catholic Ethics; Agape and the Liberation Movements. Part III. Calvin's Idea of Freedom in the Ethics of Schleiermacher and Barth; Creativity and Freedom in the Thought of Martin Buber; The Liberating Visions of C. G. Jung; 'The World's Most Perverse Habit'; Appendix: Study Questions. (shrink)

Discusses three concepts crucial to an understanding of the nature of religion: anxiety, guilt, and freedom. The various essays examine these from the viewpoint of several different religious traditions, movements and thinkers. Contents: Editor's Preface. Donald Gard: A Personal Perspective. Part I. Guiltless Morality; The Family of Changing Woman: Nature and Women in Navaho Thought; The Sacraments as 'Fear-provoking' and 'Awe-inspiring' Rites in the Greek Fathers; The Doctrine of Karma; Two Concepts of Predestination in Current Islamic Thought. Part II. The (...) Spirit of Medieval Penitents; The Evolution of Freedom as Catholicity in Catholic Ethics; Agape and the Liberation Movements. Part III. Calvin's Idea of Freedom in the Ethics of Schleiermacher and Barth; Creativity and Freedom in the Thought of Martin Buber; The Liberating Visions of C. G. Jung; 'The World's Most Perverse Habit'; Appendix: Study Questions. (shrink)

The objective of the study was to investigate the relationship between childhood IQ of parents and characteristics of their adult offspring. It was a prospective family cohort study linked to a mental ability survey of the parents and set in Renfrew and Paisley in Scotland. Participants were 1921-born men and women who took part in the Scottish Mental Survey in 1932 and the Renfrew/Paisley study in the 1970s, and whose offspring took part in the Midspan Family study in 1996. There (...) were 286 offspring from 179 families. Parental IQ was related to some, but not all characteristics of offspring. Greater parental IQ was associated with taller offspring. Parental IQ was inversely related to number of cigarettes smoked by offspring. Higher parental IQ was associated with better education, offspring social class and offspring deprivation category. There were no significant relationships between parental IQ and offspring systolic blood pressure, diastolic blood pressure, cholesterol, glucose, lung function, weight, body mass index, waist hip ratio, housing, alcohol consumption, marital status, car use and exercise. Structural equation modelling showed parental IQ associated with offspring education directly and mediated via parental social class. Offspring education was associated with offspring smoking and social class. The smoking finding may have implications for targeting of health education. (shrink)

When first confronted by the Historia Romana of Velleius Paterculus, it is easy for a reader to assume on the basis of the title and the surviving part of the text that it is a history of Rome, albeit a short one. In the following discussion I intend to demonstrate, first, why that initial assumption should be rejected and, secondly, how the work fits into the tradition of Roman historical writing.

In this paper, we describe the use of legal ontologies as a basis to improve IT support for professional judges. As opposed to most legal ontologies designed so far, which are mostly based on dogmatic and normative knowledge, we emphasize the importance of professional knowledge and experience as an important pillar for constructing the ontology. We describe an intelligent FAQ system for junior judges that intensively use the ontology.

We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters pooled data and determined that DBS expanded in its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. The DBS Think Tank was founded in 2012 providing a space where clinicians, engineers, researchers from industry and academia discuss current and emerging DBS technologies and logistical and ethical issues facing the field. (...) The emphasis is on cutting edge research and collaboration aimed to advance the DBS field. The Eighth Annual DBS Think Tank was held virtually on September 1 and 2, 2020 (Zoom Video Communications) due to restrictions related to the COVID-19 pandemic. The meeting focused on advances in: (1) optogenetics as a tool for comprehending neurobiology of diseases and on optogenetically-inspired DBS, (2) cutting edge of emerging DBS technologies, (3) ethical issues affecting DBS research and access to care, (4) neuromodulatory approaches for depression, (5) advancing novel hardware, software and imaging methodologies, (6) use of neurophysiological signals in adaptive neurostimulation, and (7) use of more advanced technologies to improve DBS clinical outcomes. There were 178 attendees who participated in a DBS Think Tank survey, which revealed the expansion of DBS into several indications such as obesity, post-traumatic stress disorder, addiction and Alzheimer’s disease. This proceedings summarizes the advances discussed at the Eighth Annual DBS Think Tank. (shrink)

Here we studied how participants steer to intercept uniformly moving targets in a virtual driving task. We tested the hypothesis that locomotor interception behavior cannot fully be explained by a strategy of nulling rate of change in pertinent agent-target relations such as the target-heading angle or target’s bearing angle. In line with a previously reported observation and model simulations, we found that, under specific combinations of initial target eccentricity and target motion direction, locomotor paths revealed reversals in movement direction. This (...) phenomenon is not compatible with unique reliance on first-order information in the case of uniformly moving targets. We also found that, as expected, such reversals in movement direction were not observed consistently over all trials of the same experimental condition: their presence depended on the timing of the first steering action effected by the participant, with only early steering actions leading to reversals in movement direction. These particular characteristics of the direction-reversal phenomenon demonstrated here for a locomotor interception-by-steering task correspond to those reported for lateral manual interception. Together, these findings suggest that control strategies operating in manual and locomotor interception may at least share certain characteristics. (shrink)

BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

DBS Think Tank IX was held on August 25–27, 2021 in Orlando FL with US based participants largely in person and overseas participants joining by video conferencing technology. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers and researchers can freely discuss current and emerging deep brain stimulation technologies as well as the logistical and ethical issues facing the field. The consensus among the DBS Think Tank IX speakers was that DBS expanded in (...) its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. After collectively sharing our experiences, it was estimated that globally more than 230,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. As such, this year’s meeting was focused on advances in the following areas: neuromodulation in Europe, Asia and Australia; cutting-edge technologies, neuroethics, interventional psychiatry, adaptive DBS, neuromodulation for pain, network neuromodulation for epilepsy and neuromodulation for traumatic brain injury. (shrink)

Humanist sociologists are activists rooted in the reality of history and change and guided by a concern for the 'real life' problems of equality, peace, and social justice. They view people as active shapers of social life, capable of creating societies in which everyone's potential can unfold. Alfred McClung Lee introduces this volume with 'Sociology: Humanist and Scientific' and develops the theme that a sociology that is humanist is also scientific. The other nine selections are grouped into four parts: 'The (...) Individual and Social Life;' 'Social Institutions: Technology, Science, and Formal Organization;' 'Political Structures: Issues of Justice and Equality;' and 'Methodological Critiques and Counterproposals.'. (shrink)

Professor Kenneth J. Arrow is one of the most distinguished economic theorists. He has played a major role in shaping the subject and is honoured by the publication of three volumes of essays on economic theory. Each volume deals with a different area of economic theory. The books include contributions by some of the best economic theorists from the United States, Japan, Israel and Europe.

Professor Kenneth J. Arrow is one of the most distinguished economic theorists. He has played a major role in shaping the subject and is honoured by the publication of three volumes of essays on economic theory. Each volume deals with a different area of economic theory. The books include contributions by some of the best economic theorists from the United Stated, Japan, Israel and Europe. This second volume is entitled Equilibrium Analysis and is divided into sections on general equilibrium and (...) on the microfoundations of macroeconomics. (shrink)

Professor Kenneth J. Arrow is one of the most distinguished economic theorists. He has played a major role in shaping the subject and is honoured by the publication of three volumes of essays on economic theory. Each volume deals with a different area of economic theory. The books include contributions by some of the best economic theorists from the United Stated, Japan, Israel and Europe. This third volume is entitled Uncertainty, Information, and Communication.

Professor Kenneth J. Arrow is one of the most distinguished economic theorists. He has played a major role in shaping the subject and is honoured by the publication of three volumes of essays on economic theory. Each volume deals with a different area of economic theory. The books include contributions by some of the best economic theorists from the United States, Japan, Israel and Europe.

Over the last fifteen years, linguists and philosophers of language have reexamined the canonical, Kratzerian semantics for modal expressions, with special attention paid to their epistemic and deontic uses. This article is an overview of the literature on deontic modal expressions. Section 1 provides an overview of the canonical semantics, noting some of its main advantages. Section 2 introduces a set of desiderata that have achieved the status of fixed points in the debates about whether the canonical semantics is correct. (...) These include the observations that deontic modal sentences have both deliberative and evaluative readings and both information-sensitive and -insensitive readings. Adequate resolutions of certain puzzles in deontic logic and resolving the Frege-Geach problem for Expressivism have also achieved this status. The third section provides an opinionated overview of some of the main extant rivals to the canonical semantics, including Cariani, Kaufmann, and Kaufmann’s (2013) complex contextualism , Yalcin’s (2012) Expressivism, Willer’s (2014) dynamic semantics, and Starr’s (2016) dynamic Expressivism. Section 4 provides an assessment of each of the views discussed in terms of the desiderata introduced in section 2. Section 5 is an overview of remaining issues that require more attention in the literature. (shrink)

“What does it mean to say that we live in a secular age?” This apparently simple question opens into the massive, provocative, and complex A Secular Age, where Charles Taylor positions secularism as a defining feature of the modern world, not the mere absence of religion, and casts light on the experience of transcendence that scientistic explanations of the world tend to neglect. -/- In Varieties of Secularism in a Secular Age, a prominent and varied group of scholars chart the (...) conversations in which A Secular Age intervenes and address wider questions of secularism and secularity. The distinguished contributors include Robert Bellah, José Casanova, Nilüfer Göle, William E. Connolly, Wendy Brown, Simon During, Colin Jager, Jon Butler, Jonathan Sheehan, Akeel Bilgrami, John Milbank, and Saba Mahmood. -/- Varieties of Secularism in a Secular Age is edited by Michael Warner, Jonathan VanAntwerpen, and Craig Calhoun. (shrink)

A leading figure in neuroaesthetics makes the case that aesthetic experience can be meaningfully measured by the tools of neuroscience.

A groundbreaking approach to martial arts combining Self-Image Psychology and Qigong. Martial arts teacher Phillip Starr draws on more than sixty years of experience to introduce the Mirror Image Technique--a method that recognizes the reinforcing nature of body and mind. Our self-image expresses in how we stand, move, and hold ourselves in the world; and in martial arts, the way we move reflects the way we think on the mat, in practice, and when sparring. Here, Starr pulls from (...) Self-Image Psychology and Qigong to offer readers a unique set of physical exercises that can be applied to any martial art tradition--as well as our personal lives. Like two mirrors facing each other, the physical body both reflects and changes the mind, and vice versa: our physical movements become more than just the consequence of our intentions or thoughts. As we adjust the way we move, we adjust the way we think: about ourselves, our lives, and our environments. Unlike other self-help books that consider the mind as the sole gateway to change, the Mirror Image Technique shows that cognitive transformation starts with the body. Starr takes readers through: Demonstrating key principles of Qigong with exercises like The Unbreakable Arm and The Unliftable Body Improving your stance Increasing your strike force Insights into the mindset for breaking boards (tameshiwari). Intended to enhance growth and personal development, the techniques in Martial Arts and the Mirror Image lead to a renewal of confidence and enthusiasm for one’s particular practice. (shrink)

A groundbreaking approach to martial arts combining Self-Image Psychology and Qigong. Martial arts teacher Phillip Starr draws on more than sixty years of experience to introduce the Mirror Image Technique--a method that recognizes the reinforcing nature of body and mind. Our self-image expresses in how we stand, move, and hold ourselves in the world; and in martial arts, the way we move reflects the way we think on the mat, in practice, and when sparring. Here, Starr pulls from (...) Self-Image Psychology and Qigong to offer readers a unique set of physical exercises that can be applied to any martial art tradition--as well as our personal lives. Like two mirrors facing each other, the physical body both reflects and changes the mind, and vice versa: our physical movements become more than just the consequence of our intentions or thoughts. As we adjust the way we move, we adjust the way we think: about ourselves, our lives, and our environments. Unlike other self-help books that consider the mind as the sole gateway to change, the Mirror Image Technique shows that cognitive transformation starts with the body. Starr takes readers through: • Demonstrating key principles of Qigong with exercises like The Unbreakable Arm and The Unliftable Body • Improving your stance • Increasing your strike force • Insights into the mindset for breaking boards (tameshiwari). Intended to enhance growth and personal development, the techniques in Martial Arts and the Mirror Image lead to a renewal of confidence and enthusiasm for one’s particular practice. (shrink)

Max Weber's distinction in "Politics as a Vocation" between the ethic of conviction and the ethic of responsibility is best understood as a distinction between mutually exclusive ethical worldviews. Interpretations that correlate the two ethics with Weber's distinction between value-rational social action and instrumental-rational social action are misleading since Weber assumes that both types of rational social action are present in both ethics. The ethic of conviction recognizes a given hierarchy of values as the context for moral endeavor. The ethic (...) of responsibility acknowledges value obligations, but assumes the absence of any given hierarchy of values and the inevitability of value conflict as the context for moral endeavor. When interpreted in the context of his multilayered understanding of value conflict, Weber's ethic of responsibility emerges as a coherent ethical perspective. (shrink)

This paper is a contribution to the study of equality-free logic, that is, first-order logic without equality. We mainly devote ourselves to the study of algebraic characterizations of its relation of elementary equivalence by providing some Keisler-Shelah type ultrapower theorems and an Ehrenfeucht-Fraïssé type theorem. We also give characterizations of elementary classes in equality-free logic. As a by-product we characterize the sentences that are logically equivalent to an equality-free one.

What happens when someone acts? A familiar answer goes like this. There is something that the agent wants, and there is an action that he believes conducive to its attainment. His desire for the end, and his belief in the action as a means, justify taking the action, and they jointly cause an intention to take it, which in turn causes the corresponding movements of the agent's body. I think that the standard story is flawed in several respects. The flaw (...) that will concern me in this paper is that the story fails to include an agent-or, more precisely, fails to cast the agent in his proper role. (shrink)

This paper presents an example of a supersimple nonlow theory and characterizes its independence relation.

Current research on construction of the female body focuses on non-Hispanic women in the United States. The idealized Latina body, however, is rapidly becoming commodified and objectified in global popular culture. Using standardized and open-ended surveys and group and individual interviews, the author examines the negotiation of sociocultural ideals and body image by adolescents at the intersection of gender, race, and beauty. These young women hold racist beauty ideals but are flexible when judging the appearance of real-life women. They perceive (...) two competing or complementary prototypes of beauty, one white and one Latina. This study fills a gap in the literature on beauty and the body by examining a non-U.S. sample that does not fit into the usual Black-white dichotomy of race. (shrink)